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Index > Protein center > Eef2k(Gene name) > Mouse
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  • Eef2k (Gene name),
  • Eukaryotic elongation factor 2 kinase (Protein name ),  EF2K_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Eef2k;
    Protein name:
    Eukaryotic elongation factor 2 kinase(eEF-2 kinase;eEF-2K);
    Alternative:
    Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer or homodimer.
    Function:
    Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    724
    Sequence:
    50:
    MADEDLIFCL | EGVDGGRCSR | AGHNADSDTD | SDDDEGYFIC | PITDDHMSNQ | 
    100:
    NVSSKVQSYY | SNLTKTECGS | TGSPASSFHF | KEAWKHAIEK | AKHMPDPWAE | 
    150:
    FHLEDIATEH | ATRHRYNAVT | GEWLKDEVLI | KMASQPFGRG | AMRECFRTKK | 
    200:
    LSNFLHAQQW | KGASNYVAKR | YIEPVDRSVY | FEDVQLQMEA | KLWGEDYNRH | 
    250:
    KPPKQVDIMQ | MCIIELKDRP | GQPLFHLEHY | IEGKYIKYNS | NSGFVRDDNI | 
    300:
    RLTPQAFSHF | TFERSGHQLI | VVDIQGVGDL | YTDPQIHTEK | GTDFGDGNLG | 
    350:
    VRGMALFFYS | HACNRICQSM | GLTPFDLSPR | EQDAVNQSTR | LLQSAKTILR | 
    400:
    GTEEKCGSPR | IRTLSSSRPP | LLLRLSENSG | DENMSDVTFD | SLPSSPSSAT | 
    450:
    PHSQKLDHLH | WPVFGDLDNM | GPRDHDRMDN | HRDSENSGDS | GYPSEKRSDL | 
    500:
    DDPEPREHGH | SNGNRRHESD | EDSLGSSGRV | CVETWNLLNP | SRLHLPRPSA | 
    550:
    VALEVQRLNA | LDLGRKIGKS | VLGKVHLAMV | RYHEGGRFCE | KDEEWDRESA | 
    600:
    IFHLEHAADL | GELEAIVGLG | LMYSQLPHHI | LADVSLKETE | ENKTKGFDYL | 
    650:
    LKAAEAGDRH | SMILVARAFD | TGLNLSPDRC | QDWSEALHWY | NTALETTDCD | 
    700:
    EGGEYDGIQD | EPQYALLARE | AEMLLTGGFG | LDKNPQRSGD | LYTQAAEAAM | 
    724:
    EAMKGRLANQ | YYEKAEEAWA | QMEE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    SMR:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse eEF-2 kinase
    Cat.:
    E11481m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse eEF-2 kinase
    Cat.:
    E11481h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse eEF-2 kinase
    Cat.:
    E11481r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse eEF-2 kinase
    Cat.:
    U11481h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse eEF-2 kinase
    Cat.:
    U11481r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse eEF-2 kinase
    Cat.:
    U11481m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse eEF-2 kinase
    Cat.:
    P11481Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse eEF-2 kinase
    Cat.:
    P11481Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse eEF-2 kinase
    Cat.:
    P11481Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse eEF-2 kinase
    Monoclonal Antibody for Mouse eEF-2 kinase
    Monoclonal Antibody for Mouse eEF-2 kinase
    Protein for Mouse eEF-2 kinase
    Protein for Mouse eEF-2 kinase
    Protein for Mouse eEF-2 kinase

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    Precision
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    Linearity
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    References
    1. 1.
      "Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase."
      Ryazanov A.G. , Ward M.D. , Mendola C.E. , Pavur K.S. , Dorovkov M.V. , Wiedmann M. , Erdjument-Bromage H. , Tempst P. , Parmer T.G. , Prostko C.R. , Germino F.J. , Hait W.N.
      Proc. Natl. Acad. Sci. U.S.A.94:4884-4889(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CATALYTIC ACTIVITY;FUNCTION
      strain: BALB/c.
      tissue: Spleen.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      tissue: Mammary gland.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-70;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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